Real-world evidence generation + analytics

Real-world data is exponentially gaining importance in evaluating novel treatments in the regulatory and reimbursement landscapes. Our real-world evidence generation and analytics team specializes in generating a wide range of clinical, economic, and quality of life evidence to support effective internal decision making as well as HTA reimbursement decision-making.

We conduct prospective, retrospective, and cross-sectional studies, as well as key opinion leader research, to help develop insights to complement current clinical trial practice.  We offer a complete range of evidence generation activities to support treatment placement, barriers in access and use of treatments, among many other important research domains.

Our evidence generation services include, but are not limited to:

• Burden of illness
• Healthcare resource utilization
• Healthcare resource costs
• Treatment patterns
• Adherence and persistence
• Epidemiology
• Clinician and stakeholder interviews and focus groups

While we do not possess in-house real-world data, our team has recognized expertise in the analyses of administrative databases and electronic medical records. Additionally, our team has intimate knowledge of and access to real-world data in Canada through our partners.

Our sophisticated analytical services for real-world data include, but are not limited to:

• Synthetic cohort analyses
• Pragmatic clinical trials
• Target trial emulation
• External and historical comparators
• Quantitative bias analysis
• Propensity score (PS), power prior (PP), and composite likelihood (CL) approaches